Chronic venous insufficiency such as varicose veins, itching, pain and a sensation of heaviness legs,nocturnal cramps in the calves and swelling of the leg
Strengthen and repair blood vessels that have lost their elasticity
Triterpene glycoside mixture (aescin) has an anti-exudative, vascular tightening effect and inhibits filtration of small molecule proteins, electrolytes and water into the interstitium by vascular permeability reduction and improvement of venous return flow, which prevents both and improves hemorrhoids and varicose veins.
– Horse chestnut seed extract reduces the activity of lysosomal enzymes, which increases in chronic pathological conditions of the veins, thereby preventing breakdown of mucopolysaccharides in the region of the capillary wall and inhibiting proteins to leak into the interstitium.
Each tablet contains 250 mg Aesculus hippocastanum (horse chestnut) seed extract standardized on 50 mg triterpene glycoside as aescin.
The main principles are triterpene saponins, hydroxycoumarins, flavonoids and a rich supply of tannins.
ADMINISTRATION AND DOSAGE
Take 2 tablets daily (morning and evening)after meal and with a glass of water.
There is no documented interactions.
Health risks or side effects following the proper administration of designated therapeutic dosages are not recorded.
Pruritis, nausea and gastric complaints occuring after oral intake, can be reduced by taking tablets with the main meal.
CONTRAINDICATIONS & PRECAUTIONS
Not recommended for children or for patients with chronic renal diseases.
PREGNANCY AND LACTATION
The product should not be used during pregnancy and lactation due to insufficient data.
Store below 30˚C and protect from light and moisture.
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3-The ABC clinical guide to herbs, 2003, 250-254.
4-MacKay D. Hemorrhoids and varicose veins: a review of treatment options. Alternative medicine review. 2001. 6(2):126-40.
5-Rothkopf M, Vogel G. New findings on the efficacy and mode of action of the horse chestnut saponin escin. Arzneimittelforschung. 1976. 26(2):225-35.
6-Dickson S., Gallagher J., McIntyre L., Suter A., Tan J. An open study to assess the safety and efficacy of Aesculus hippocastanum tablets (Aesculaforce 50 mg) in the treatment of chronic venous insufficiency. Herbal pharmacotherapy. 2003. 2:19-32.
7-Suter A., Silvia B., Rechner J. Treatment of patients with venous insufficiency with fresh plant horse chestnut seed extract: A review of 5 clinical studies. Advances in therapy. 2006. 23(1): 179-190.