Femodin tablet

Improvement of PMS , Menstrual Irregularities & Menopause complaints

Dosage form and packaging:

Each box contains 50 coated tablets.

Description

Indications:

Premenstrual Syndrome (PMS)

Irregular menstrual periods

Breast tenderness and pain (Mastalgia)

Painful periods (Dysmenorrhea)

Hyperprolactinemia

Menopause symptoms

PHARMACOLOGIC ACTIONS

The results of clinical tests have shown that the products which contain 20 mg  vitex extract can be effective on irregularity of menstrual period such as: oligomenorrhea,  polymenorrhea, menorrhagia, amenorrhea, and Premenstrual Syndrome (PMS) that include: headache, breast tenderness, bloat, fatigue, changes in appetite, anger, sadness, hopelessness, feelings of worthlessness and variable moods. The research about mechanism of vitex extract action has shown it work on pituitary gland by D2 receptor and decrease prolactin level so can cause improvement in hyperprolactinemia. In addition, vitex extract can work as corpus luteum hormone that inhibit FSH and stimulate LH release and as the result increase estrogen and decrease progesterone level. Moreover result from several studies has shown that vitex extract is helpful for acne (that cause before menstrual periods) treatment. This product with dopaminergic effect can improve mental disorders, sleeping irregularity and physical disorders of menopause such as hot flushes.

ACTIVE INGREDIENTS

Standard and dry total extract of Vitex agnus-castus: 20 mg per tablet

ADMINISTRATION AND DOSAGE

Take 1 tablet half an hour before breakfast.

INTERACTIONS

There is no document about this medicine interaction in recommended dose.

ADVERSE REACTIONS

Rarely causes headache, fatigue, nausea and dry mouth (1-2%).

CONTRAINDICATIONS & PRECAUTIONS

Not reported.

PREGNANCY AND LACTATION

This medicine is contra-indicated during pregnancy and lactation.

TIPS

Check with your pharmacist or doctor if you take any OCP (Birth Control Pills).

STORAGE

Store below 30°C and protect from light and moisture.

IRC

1228236990

REFERENCES

1- PDR for herbal medicines,(2004),186-188.

2- The ABC Clinical Guide to herbs,(2003), 63-72. .

3- European Scientific cooperative on phytotherapy(E/S/C/O/P monographs), second edition(2003), 8-13

4- Diana van Die M.et al.(2009). Vitex agnus- castus (chaste-tree/ Berry) in the treatment of menopause-Related complaints. THE JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINE, 15(8),853-859.

5- Diana van Die M.et al. (2012). Vitex agnus-castus Extracts for female Reproductive Disorders: A systematic of clinical Trials . Planta med 2013, 79, 562-575.

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